Background: Prostate cancer is the third leading cause of death and is the most common cause of cancer in elderly men. Regarding to the low accuracy of screening methods such as prostate-specific antigen (PSA), Digital Rectal Examination (DRE) and trans rectal ultrasound (TRUS) in detection and localization of tumor, Magnetic Resonance Imaging (MRI) and Diffusion Weighted Imaging (DWI) attracted many attentions in the past years. DWI reveals micro-molecular Diffusion, which is the Brownian motion of the spins in biologic tissues. This technique can delineate pathologic lesions with high tissue contrast against generally suppressed background signal. In this paper, the value of DWI in detection of prostate cancer is studied.Methods: In this cross-sectional study, the studied population are suspicious patients to prostate cancer based on high Prostatic Specific Antigen level or abnormal Digital Rectal Examination who refered for prostate biopsy to radiology department of Hazrate- Rasoul Hospital during the year 2011. The results of DWI are compared to biopsy results for all patients.Results: Eighty five patients are selected. The DWI sensitivity in detecting of prostate cancer is 100%, specificity 97.1% and positive and negative predictive values are 89.5% and 100%, respectively. The results showed that if DWI reports the prostate cancer as negative, the result was highly reliable and if it reports as positive, although the report was not 100% reliable, but it still had high reliability, more than 90%.Conclusion: DWI had high accuracy in detecting prostate cancer for patients with cancer. Also the accuracy of this method for patients without prostate cancer was acceptable compared to the other common methods.

Background: Multiple sclerosis (MS) is a chronic disease that begins most commonly in young adults and is characterized pathologically by multiple areas of central nervous system (CNS) white matter inflammation, demyelination, and glial scarring. The most valuable aid for diagnosis is magnetic resonance imaging (MRI). New type of MRI has been developed on the basis of molecular Diffusion which capable of detecting acute and active lesions. Early diagnosis and treatment is possible to stop or slowdown progression of disease. The aim of this study is to compare the findings of conventional and Diffusion- weighted (DW) MRI in detection cerebral lesions of MS.Methods: Thirty patients with clinically definite MS and 30 healthy volunteers were studied in a descriptive-prospective survey over a twelve-month period of time.Conventional and DW MRI were used in both groups. Total number, morphology, location and the mean size of the intra-cerebral plaques of MS were compared between group. The sensitivity and the specificity of both imaging methods in detecting these plaques were determined.Results: Thirty patients with MS with the mean age of 32.76±8.79 years and 30 healthy individuals with the mean age of 32.75±9.23 years were enrolled. Plaque within the brain was significantly higher by the conventional method (P<0.05). Ovoid lesions were greater in number in the conventional method group. More lesions were detected by the conventional method in the areas of periventricle, centrum semiovale and corpus callosum. Regarding the size of plaque, the minimum measurement was significantly lower in the conventional method group. The sensitivity of both methods was 100%. The specificity of conventional and DW MRI was 86.6% and 96.6%, respectively.Conclusion: In our study the sensitivity of both methods was the same but the specificity of DW MRI was higher. DW MRI may detect lesions which are not detectable by the routine methods.

Introduction The staging of endometrial carcinoma is now performed based on postoperative pathological assessments. If the staging of the cancer could be possible with a preoperative non-invasive method, based on the International Federation of Gynecology and Obstetrics system, a more appropriate treatment protocol can be recommended for patients. This study was performed aimed to evaluate the diagnostic value of dynamic magnetic resonance imaging with Diffusion-weighted imaging in the staging of endometrial carcinoma, based on the postoperative histopathological reference standard. Methods This prospective study was conducted in 2016-2021 on 35 patients with endometrial cancer referred to Ghaem Hospital in Mashhad. The staging of endometrial cancer was performed based on MRI findings and pathological samples. The diagnostic value of MRI was calculated to distinguish stages 1 from 2 and 1A from 1B. The lesion dimensions in the MRI and the pathological samples were compared using independent-sample t-test and the lesion dimensions between different stages using the ANOVA test by SPSS (version 17). P<0. 05 was considered statistically significant. Results According to the findings of MRI and pathology, the majority of patients (93. 3%) were in stage 1, and 2 (6. 7%) were in stage 2. The sensitivity, specificity, positive and negative predictive value in differentiating stage 1 from stage 2 was 100%, and the sensitivity, specificity, positive and negative predictive value of MRI in differentiating IA from IB was 100%. Conclusion It seems that dMRI by DWI method can be used in the staging of endometrial tumors in the initial stages (stage 1 from 2 and IA from IB) with diagnostic value.

Band structure of porous alumina photonic crystal in the G X direction was calculated using order-N method. In a comparison of calculated results with experimental data of reflective and absorptive index, the variation of refractive index of alumina in the external region of oxide layer, around the pores were studied. A Gaussian distribution Function was adopted for phosphate anions in the external oxide layer and the variation of refractive index and Diffusion depth were determined. The structure of the first four bands was calculated using the obtained distribution of refractive index in the external oxide layer for both TE and TM mode. This results show a narrow full band gap in the TM mode.

A characteristic of Data Envelopment Analysis (DEA) is to allow individual decision making units (DMUs) to select the factor weights which are the most advantageous for them in calculating their efficiency scores. This flexibility in selecting the weights, on the other hand, deters the comparison among DMUs on a common base. For dealing with this difficulty and assessing all the DMUs on the same scale, this paper proposes using a multiple objective linear programming (MOLP) approach based on scalarizing Function for generating common set of weights under the DEA framework. This is an advantageous of the proposed approach against general approaches in the literature which are based on multiple objective nonlinear programming.

Background: Based on the studies which have been done till now, resynchronization of ventricular contraction results in clinical improvement in patients who suffer from moderate to severe heart failure with intraventricular conduction disturbance. and using this method is increasing in our country. Study in this filed seems to be necessary.Material and methods: Sixty-five consecutive patients with advanced heart failure, NYHA Class III and IV, LV ejection fraction (EF)£35%, QRS³120 were studied before and 3 months after CRT. Mean age was 60, 57 and 8 patients with NYHA class III and IV respectively. All patients received furosemide, spironolactone, carvedilol, ACE inhibitors and angiotensin II –receptors blockers at the optimal tolerated dosage. Mean LVEF was 20.83%. Echocardiographic (Tissue Doppler Imaging), ECG and Function class (NYHA) were assessed at baseline before implantation and 3 months after.Result: LV ejection fraction increased +6.8% (21.10±7 vs. 27.93±8.4%, P<0.001). Mitral valve regurgitation severity reduced (P<0.013). Interventricular mechanical delay reduced (53.83ms±18.45 vs. 26.53ms±13.90 P=0.000) and also Intra ventricular mechanical delay reduced (62.53ms±25.08 vs. 45.55ms±13.47, P=0.000). Dilated cardiomyopathic group has more mean changes in LVEF than Ischemic group (+9.06%±7.3 vs. +4.08%±6.5, P=0.01).Conclusion: Biventricular pacing results in significant clinical improvement in patients who have moderate to severe heart failure.